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PI 103 hydrochloride, Tocris Bioscience™

Product Code. 18095252
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Quantity:
1 mg
10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Inhibitor of PI 3-kinase, mTOR and DNA-PK

Inhibitor of DNA-PK, PI 3-kinase (p110α) and mTOR (IC50 values are 2, 8, 20, 26, 48, 83, 88, 150, 850, 920, ∽ 1000 and 2300 nM for DNA-PK, p110α, mTORC1, PI 3-KC2β, p110δ, mTORC2, p110β, p110γ, ATR, ATM, PI 3-KC2α and hsVPS34 respectively). Inhibits growth of human tumor xenografts in mice in vivo. Induces autophagosome formation in glioma cells.

Chemical Identifiers

CAS 371935-79-4
Molecular Formula C19H17ClN4O3
Molecular Weight (g/mol) 384.82
InChI Key XSQMYBFFYPTMFE-UHFFFAOYSA-N
Synonym pi 103 hydrochloride, pi-103 hydrochloride, pi103 hydrochloride, pubchem22442, pi-103, hydrochloride, c19h16n4o3.clh, pi 103 hydrochloride;pi103 hydrochloride, 3-4-morpholinopyrido 3',2':4,5 furo 3,2-d pyrimidin-2-yl phenol hydrochloride, 3-4-4-morpholinylpyrido 3',2':4,5 f uro 3,2-d pyrimidin-2-yl phenol hydrochloride
PubChem CID 16739368
IUPAC Name 3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin-2-yl)phenol;hydrochloride
SMILES C1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)O.Cl

Specifications

Quantity 1 mg
Formula Weight 384.82
Percent Purity >98%
Chemical Name or Material PI 103 hydrochloride
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