Thermo Scientific™ LC-SMCC (succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxy-(6-amidocaproate))

Crosslink amines to sulfhydryls with this long crosslinker composed of NHS-ester and maleimide groups at ends of a stabilizing cyclohexane-containing, 15-atom spacer arm.

Brand:  Thermo Scientific™ 22362

Product Code. 11831305

Description

Thermo Scientific™ Pierce LC-SMCC is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a long cyclohexane-stabilized spacer arm (16.2 Ås)

Highlights:

• Ideal for coupling enzymes to antibodies as both enzyme activity and antibody specificity can be preserved after coupling
• Cyclohexane-containing spacer stabilizes the maleimide group
• Useful for the preparation of stable maleimide-activated proteins
• Reactive groups: NHS ester and maleimide
• Reactive toward: amino and sulfhydryl groups

Specifications

• Chemical Reactivity: Amine-Sulfhydryl
• Description: LC-SMCC
• PEGylated: No
• Content And Storage: Upon receipt store desiccated at 4°C.
• Shipping Condition: Ambient
• Labeling Method: Chemical Labeling
• Reactive Moiety: Maleimide, NHS Ester
• Form: Solid
• Solubility: DMF, DMSO
• Water Soluble: No

• Cleavable: No
• Molecular Weight (g/mol): 447.48
• Spacer Arm Length: 16.2 Å
• Cell Permeability: Yes
• Product Line: Pierce™
• Crosslinker Type: Heterobifunctional
• Spacer: Medium (10 to 30 Å)
• Quantity: 50 mg
• Format: Standard
• Product Type: Crosslinker

For Research Use Only. Not for use in diagnostic procedures.