TC-E 5005, Tocris Bioscience™

Description

Potent and selective PDE10A inhibitor

Potent and selective PDE10A inhibitor (IC50 values are 7.28, 239, 779, 919, 3100 and 3700 nM at PDE10A, 2A, 11A, 5A, 7B and 3A respectively and >5000 nM at PDE1B, 4A, 6, 8A and 9A). Reverses MK 801-induced hyperactivity in vivo.

Specifications

Chemical Identifiers

• CAS: 959705-64-7
• Molecular Formula: C15H18N4O
• Molecular Weight (g/mol): 270.336
• InChI Key: YNADXFWEXJTQSZ-UHFFFAOYSA-N
• Synonym: 2-methoxy-6,7-dimethyl-9-propylimidazo 1,5-a pyrido 3,2-e pyrazine, 2-methoxy-6,7-dimethyl-9-propyl-imidazo 1,5-a pyrido 3,2-e pyrazine, 3,4-dimethyl-8-methoxy-1-propyl-imidazo 1,5-a pyrido 3,2-e pyrazine, imidazo 1,5-a pyrido 3,2-e pyrazine,2-methoxy-6,7-dimethyl-9-propyl, 12-methoxy-5,7-dimethyl-3-propyl-2,4,8,13-tetraazatricyclo 7.4.0.0 2 ,? trideca-1 13 ,3,5,7,9,11-hexaene
• PubChem CID: 24802717
• SMILES: CCCC1=NC(=C2N1C3=C(C=CC(=N3)OC)N=C2C)C

• Quantity: 10 mg
• Formula Weight: 270.33
• Percent Purity: >99%
• Chemical Name or Material: TC-E 5005