VU 152100, Tocris Bioscience™

Description

Positive allosteric modulator of M4 receptors

Selective positive allosteric modulator of M4 muscarinic acetylcholine receptors (mAChRs) (EC50 = 380 nM). Induces 21-fold shift in ACh potency at M4 receptor. Displays no activity at other mAChR subtypes.

Spécification

Identifiants chimiques

• CAS: 409351-28-6
• Molecular Formula: C18H19N3O2S
• Molecular Weight (g/mol): 341.429
• InChI Key: MDNWGCQSCGNTKH-UHFFFAOYSA-N
• Synonym: 3-amino-n-4-methoxyphenyl methyl-4,6-dimethylthieno 2,3-b pyridine-2-carboxamide, 3-amino-n-4-methoxybenzyl-4,6-dimethylthieno 2,3-b pyridine carboxamide, kinome_1269, d0k3hy, vu hplc, 3-amino-4,6-dimethyl-n-p-anisyl-thieno 2,3-b pyridine-2-carboxamide, 3-amino-4,6-dimethylthiopheno 2,3-b pyridin-2-yl-n-4-methoxyphenyl methyl carboxamide, 3-amino-n-4-methoxyphenyl methyl-4,6-dimethyl-2-thieno 2,3-b pyridinecarboxamide, 3-amino-n-4-methoxyphenyl methyl-4,6-dimethyl-thieno 2,3-b pyridine-2-carboxamide, 3-amino-n-4-methoxyphenyl methyl-4,6-dimethylthieno 5,4-b pyridine-2-carboxamide
• PubChem CID: 864492
• IUPAC Name: 3-amino-N-[(4-methoxyphenyl)methyl]-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
• SMILES: CC1=CC(=NC2=C1C(=C(S2)C(=O)NCC3=CC=C(C=C3)OC)N)C

• Quantity: 10 mg
• Formula Weight: 341.43
• Percent Purity: >98%
• Chemical Name or Material: VU 152100