Tocris Bioscience™ AZ 10397767

Potent CXCR2 antagonist

Product Code	Brand	Quantity
18777686	Tocris Bioscience™ 5872/10	10 mg
18797936	Tocris Bioscience™ 5872/50	50 mg

Description

Potent CXCR2 antagonist (IC50 = 1 nM); attenuates oxaliplatin -induced NF-κB activation, increases oxaliplatin cytotoxicity, and potentiates oxaliplatin-induced apoptosis in AIPC cells. Reduces the numbers of neutrophils infiltrating into tumors in both in vitro and in vivo models and delayed tumor growth. Orally bioavailable.

Specifications

• Product Type: Antagonist
• CAS: 333742-63-5
• Formula Weight: 400.88g/mol
• For Use With (Application): Chemokine Receptor Antagonists

• Target Proteins: Chemokine Receptor
• Molecular Formula: C₁₅H₁₄ClFN₄O₂S₂
• Content And Storage: Store at -20°C

For Research Use Only