Gibco™ Human/Mouse/Rat Irisin Recombinant Protein, PeproTech®

Recombinant Protein

Brand:  Gibco™ 100-65-2UG

Product Code. 17841653

Description

Recombinant Human/Murine/Rat Irisin, appears to form a non-disulfide linked oligomeric structure in solution, has a calculated theoretical molecular weight of 25.2 kDa, but migrates at an apparent molecular weight of 28 kDa by SDS-PAGE analysis under reducing conditions due to glycosylation. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Fibronectin type III domain-containing protein 5, the precursor of irisin, is a protein that is encoded by the FNDC5 gene. This gene encodes a secreted protein that is released from muscle cells during exercise. The encoded protein may participate in the development of brown fat. Translation of the precursor protein initiates at a non-AUG start codon at a position that is conserved as an AUG start codon in other organisms. Alternative splicing results in multiple transcript variants.

Specifications

• Accession Number: Q8K3V5, Q8K4Z2, Q8NAU1
• Formulation: protein with no preservative
• Molecular Weight (g/mol): 25.2 kDa
• Quantity: 2 μg
• Regulatory Status: RUO
• Gene Alias: 1500001L03Rik; AI836596; C87088; fibronectin type III domain containing 5; fibronectin type III domain-containing protein 5; Fibronectin type III repeat-containing protein 2; Fndc5; Frcp2; Irisin; PeP; Peroxisomal protein; Pxp
• Gene Symbol: FNDC5
• Conjugate: Unconjugated
• Sequence: DSPSAPVNVT VRHLKANSAV VSWDVLEDEV VIGFAISQQK KDVRMLRFIQ EVNTTTRSCA LWDLEEDTEY IVHVQAISIQ GQSPASEPVL FKTPREAEKM ASKNKDEVTM KE
• Expression System: CHO cells
• Purity or Quality Grade: ≥ 90% by SDS-PAGE gel and HPLC analyses.

• For Use With (Application): Functional Assay
• Gene ID (Entrez): 252995, 260327, 384061
• Name: Human/Mouse/Rat Irisin
• Source: CHO cells
• Endotoxin Concentration: <1 EU/ μg
• Common Name: FNDC5
• Biological Activity: Determined by its ability to promote cell survival and growth of rat H9c2 cardio-myoblasts under serum starvation conditions.
• Recombinant: Recombinant
• Content And Storage: -20°C
• Form: Lyophilized