Molecular Probes™ Probenecid, Water Soluble

Probenecid, Water Soluble

Brand:  Molecular Probes™ P36400

Product Code. 11529306

Description

Probenecid is commonly used to inhibit organic-anion transporters located in the cell membrane. Such transporters can extrude dyes and indicators and thus contribute to poor loading or a high background signal in assays based on retention of the dyes or indicators inside cells. The use of probenecid to block the efflux of intracellular dyes was first described by Di Virgilio et al. (1990), and it has been used with a wide range of anionic dyes and conjugates. The commonly used free acid form of probenecid is difficult to dissolve, requiring 1 M NaOH to get it into solution. Our water-soluble probenecid (P36400) dissolves quickly in assay buffer and eliminates the need to handle caustic NaOH. The water-soluble probenecid is included in the Fluo-4 NW Calcium Assay Kits (F36205, F36206) and is also available separately.

Specifications

• Quantity: 10 x 77 mg
• Shipping Condition: Room Temperature
• Physical Form: Solid
• Product Type: Cell Labeling Reagent

Safety and Handling

Product Identifier

• PROBENECID, WATER SOLUBLE Probenecid is commonly used to inhibit

Signal Word

• Warning

Hazard Category

• Acute toxicity Category 4

Hazard Statement

• H302-Harmful if swallowed.

Precautionary Statement

• P264-Wash hands thoroughly after handling.
• P270-Do not eat, drink or smoke when using this product.
• P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
• P330-Rinse mouth.
• P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.

Supplemental information

• MIXTURE LIST-Contains : Probenecid

For Research Use Only. Not for use in diagnostic procedures.