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USP49 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA556417
304.68 GBP valid until 2025-03-21
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Description
Immunogen sequence: ECFLNLDPSK TEHLFPKATN GKTQLSGKPT NSSATELSLR NDRAEACERE GFCWNGRASI SRSLELIQNK EPSSK Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 68%.
Specifically deubiquitinates histone H2B at 'Lys-120' (H2BK120Ub). H2BK120Ub is a specific tag for epigenetic transcriptional activation and acts as a regulator of mRNA splicing. Deubiquitination is required for efficient cotranscriptional splicing of a large set of exons.
Specifications
USP49 | |
Polyclonal | |
Unconjugated | |
USP49 | |
C330046L10Rik; deubiquitinating enzyme 49; Gm545; RGD1310513; ubiquitin carboxyl-terminal hydrolase 49; ubiquitin specific peptidase 49; ubiquitin specific protease 49; ubiquitin thioesterase 49; ubiquitin thiolesterase 49; ubiquitin-specific-processing protease 49; Usp49 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
25862 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry, Western Blot | |
0.3 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
Q70CQ1 | |
USP49 | |
Recombinant protein corresponding to Human USP49 | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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