HX 531, Tocris Bioscience™

Description

Potent RXR antagonist

Potent RXR antagonist (IC50 = 18 nM). Promotes white and brown pre-adipocyte differentiation into white adipocytes. Also inhibits bexarotene -induced brown adipogenic reprogramming of myoblasts.

Specifications

Chemical Identifiers

• CAS: 188844-34-0
• Molecular Formula: C29H29N3O4
• Molecular Weight (g/mol): 483.568
• InChI Key: SXKPGYKPQPYJER-UHFFFAOYSA-N
• Synonym: d02yhd, z-4-5,7,7,10,10-pentamethyl-2-nitro-7,8,9,10-tetrahydro-5h-benzo b naphtho 2,3-e 1,4 diazepin-12-yl benzoic acid, 4-5,7,7,10,10-pentamethyl-2-nitro-7,8,9,10-tetrahydro-5h-5,13-diaza-benzo 4,5 cyclohepta 1,2-b naphthalen-12-yl-benzoic acid, 4-5,7,7,10,10-pentamethyl-2-nitro-8,9-dihydronaphtho 2,3-b 1,5 benzodiazepin-12-yl benzoic acid, 4-7,8,9,10-tetrahydro-5,7,7,10.10-pentamethyl-2-nitro-5h-benzo b naphtho 2,3-e 1,4-diazepin-12-yl-benzoic acid
• PubChem CID: 11755040
• IUPAC Name: 4-(5,7,7,10,10-pentamethyl-2-nitro-8,9-dihydronaphtho[2,3-b][1,5]benzodiazepin-12-yl)benzoic acid
• SMILES: CC1(CCC(C2=C1C=C3C(=C2)N(C4=C(C=C(C=C4)[N+](=O)[O-])N=C3C5=CC=C(C=C5)C(=O)O)C)(C)C)C

• Quantity: 10 mg
• Formula Weight: 483.56
• Percent Purity: >98%
• Chemical Name or Material: HX 531