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Crosslinking, Labeling and Protein Modification

Crosslinking, Labeling and Protein Modification

A variety of reagents used to modify proteins for identification, analysis, research, and other applications.
Protein Labeling Reagents (6)
Tandem Mass Tag Reagents (4)
Crosslinking Reagents (2)
Protein Modification Reagents (2)

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1 – 12 of 12 results
1

Thermo Scientific™ 1M TEAB and 50% Hydroxylamine Buffers for TMT Experiments

Common TMT buffers such as 1M Triethylammonium bicarbonate (TEAB) and 50% Hydroxylamine for isobaric mass tag labeling experiments.

Content And Storage Store protected from direct sunlight in a dry, cool, and well-ventilated area.
Workflow Step Protein Labeling
Product Type Buffer
Starting Material Cell Lysate
Product Line TMT™
2

Invitrogen™ Click-iT™ Cell Reaction Buffer Kit
GREENER_CHOICE

Clicks the two moieties together

3

Invitrogen™ Click-iT™ Protein Reaction Buffer Kit
GREENER_CHOICE

Click two moieties together: azide or alkyne and the corresponding click detection reagent

4

Thermo Scientific™ TMT™ Elution Buffer and Anti-TMT Resin

For enhanced enrichment, use Thermo Scientific TMT Elution Buffer with Immobilized Anti-TMT Resin for peptides that have been chemically labeled with Tandem Mass Tag (TMT) Isobaric Label Reagents for multiplexed protein quantitation using tandem mass spectrometry.

Workflow Step Protein Labeling
Label or Dye Tandem Mass Tag™ (TMT) Labels
Starting Material Cell Lysate
Detection Method Mass Spectrometry
Product Line TMT™
5

Thermo Scientific™ Pierce™ DSG, No-Weigh™ Format

Promotions are available
EDGE
Description DSG
Cleavable No
Water Soluble No
Form Powder
Molecular Weight (g/mol) 326.26
Solubility DMF, DMSO
Labeling Method Chemical Labeling
Crosslinker Type Homobifunctional
Chemical Reactivity Amine-Amine
Cell Permeability Yes
Format Standard, Single-use
Product Type Crosslinker
Spacer Short (<10 Å)
Reactive Moiety NHS Ester
Spacer Arm Length 7.7 Å
PEGylated No
6

Thermo Scientific™ Sulfo-SMCC (sulfosuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate), No-Weigh™ Format

Crosslink amines to sulfhydryls with this mid-length, water-soluble crosslinker made of NHS-ester and maleimide groups at ends of a cyclohexane-containing, 8-atom spacer arm.

EDGE
Shipping Condition Ambient
Content And Storage Upon receipt store desiccated at -20°C.
Description Sulfo-SMCC
Cleavable No
Water Soluble Yes
Molecular Weight (g/mol) 436.37
Solubility Water
Labeling Method Chemical Labeling
Crosslinker Type Heterobifunctional
Chemical Reactivity Amine-Sulfhydryl
Cell Permeability No
Format Standard, Single-use, Premium-grade
Product Type Crosslinker
Spacer Short (<10 Å)
Reactive Moiety Maleimide, Sulfo-NHS Ester
Spacer Arm Length 8.3 Å
PEGylated No
7

Molecular Probes™ BODIPY™ TR Cadaverine (5-(((4-(4,4-Difluoro-5-(2-Thienyl)-4-Bora-3a,4a-Diaza-s-Indacene-3-yl)phenoxy)acetyl)amino)pentylamine, Hydrochloride)

BODIPY™ TR Cadaverine (5-(((4-(4,4-Difluoro-5-(2-Thienyl)-4-Bora-3a,4a-Diaza-s-Indacene-3-yl)phenoxy)acetyl)amino)pentylamine, Hydrochloride)

8

Thermo Scientific™ EZ-Link™ Sulfo-NHS-Biotin

Thermo Scientific™ EZ-Link™ Sulfo-NHS-Biotin is a short-chain, water-soluble biotinylation reagent for labeling antibodies, proteins and other molecules that have primary amines.

EDGE
Cell Permeability Cell-Impermeant
Product Type Sulfo-NHS-Biotin
Spacer Short
Label or Dye Biotin
Solubility DMF (Dimethylformamide),DMSO (Dimethylsulfoxide),Water
Chemical Reactivity Amine
Product Line EZ-Link™
9

Thermo Scientific™ DTNB (Ellman's Reagent) (5,5-dithio-bis-(2-nitrobenzoic acid)

Measure peptide cysteines or other free, reduced sulfhydryls (-SH groups) in solution using this thiol-reactive, colored compound (Amax 412nm).

Promotions are available
10

Thermo Scientific™ EZ-Link™ Sulfo-NHS-LC-Biotin

Thermo Scientific™ EZ-Link™ Sulfo-NHS-LC-Biotin is an intermediate-length, water-soluble biotinylation reagent for labeling antibodies, proteins and other molecules that have primary amines.

EDGE
Cell Permeability Cell-Impermeant
Product Type Sulfo-NHS-LC-Biotin
Spacer Mid-length
Label or Dye Biotin
Solubility DMF (Dimethylformamide),DMSO (Dimethylsulfoxide),Water
Chemical Reactivity Amine
Product Line EZ-Link™
12

Thermo Scientific™ Pierce™ DTT (Dithiothreitol)

Thermo Scientific™ Pierce™ DTT (Dithiothreitol) No-Weigh™ Format is designed for convenient preparation of stocks that will be added to protein samples for effective reduction of disulfide bonds.