5-Bromo-5-nitro-1,3-dioxane, 98%, Thermo Scientific Chemicals

Description

5-Bromo-5-nitro-1,3-dioxane, also known as bronidox, shows antimicrobial activity against gram-negative and gram-positive bacteria, yeast, and fungi.

5-Bromo-5-nitro-1,3-dioxane is used as a stabilizer and preserving agent for biological molecules and solutions such as antibodies and antisera. Bronidox is used in a variety of rinse-off cosmetic. It can be used alone or in combination with methylisothiazolone.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• 5-Bromo-5-nitro-1,3-dioxane is a chemical compound showing antimicrobial activity against gram-negative and gram-positive bacteria, yeast, and fungi
• This compound is capable of promoting the oxidation of essential protein thiols, causing inhibition of enzyme activity leading to the inhibition of microbial growth

Application

• 5-Bromo-5-nitro-1,3-dioxane has been used as a stabilizer and preserving agent for biological molecules and solutions, including antibodies and antisera
• It can be used alone or combined with methylisothiazolinone, which is also considered to be an effective preservative

Specifications

Chemical Identifiers

• CAS: 30007-47-7
• Molecular Formula: C4H6BrNO4
• Molecular Weight (g/mol): 211.999
• MDL Number: MFCD00101855
• InChI Key: XVBRCOKDZVQYAY-UHFFFAOYSA-N
• Synonym: bronidox, 1,3-dioxane, 5-bromo-5-nitro, 5-bromo-5-nitro-m-dioxane, unii-u184i9qbnm, 5-brom-5-nitro-1,3-dioxan, m-dioxane, 5-bromo-5-nitro, 5-brom-5-nitro-1,3-dioxan german, u184i9qbnm, bronidox l, acmc-209hcf
• PubChem CID: 1807
• IUPAC Name: 5-bromo-5-nitro-1,3-dioxane
• SMILES: C1C(COCO1)([N+](=O)[O-])Br

• Melting Point: 58°C to 61°C
• Color: White
• Quantity: 25 g
• Solubility Information: Soluble in water at 12.5mg/ml
• Formula Weight: 212
• Percent Purity: 98%
• Physical Form: Powder
• Chemical Name or Material: 5-Bromo-5-nitro-1,3-dioxane

Safety and Handling

Product Identifier

• 5-Bromo-5-nitro-1,3-dioxane

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 4
• LONG-TERM AQUATIC HAZARD Chronic 1
• ACUTE AQUATIC Acute 1
• Serious eye damage/eye irritation Category 1
• Skin corrosion/irritation Category 1 A

Hazard Statement

• H302-Harmful if swallowed.
• H314-Causes severe skin burns and eye damage.
• H318-Causes serious eye damage.
• H400-Very toxic to aquatic life.
• H410-Very toxic to aquatic life with long lasting effects.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.

Supplemental information

• MIXTURE LIST-Contains : 5-Bromo-5-nitro-1,3-dioxane

RUO – Research Use Only