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Bioactive Small Molecules

Bioactive Small Molecules

A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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1 – 15 of 2,174 results
3

Invitrogen™ Bis-ANS (4,4'-Dianilino-1,1'-Binaphthyl-5,5'-Disulfonic Acid, Dipotassium Salt)

Binds with affinity that is often orders-of-magnitude higher than 1-8-ANS as probe for nonpolar cavities in proteins

4

Invitrogen™ BODIPY™ 493/503 (4,4-Difluoro-1,3,5,7,8-Pentamethyl-4-Bora-3a,4a-Diaza-s-Indacene)

BODIPY™ 493/503 can be used as a stain for neutral lipds, and as a tracer for oil and other nonpolar lipids.

Promotions are available
5

Tocris Bioscience™ H 151

STING antagonist

Target STING Antagonists
CAS 941987-60-6
Purity 98%
Chemical Name or Material N-(4-Ethylphenyl)-N'-1H-indol-3-yl-urea
Recommended Storage Store at 4°C
Synonym ERIS, hMITA, MITA, mitochondrial mediator of IRF3 activation, MPYS, NET23, N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner, sting, transmembrane protein 173
Molecular Formula C17H17N3O
Formula Weight 279.34
6

Tocris Bioscience™ CMA

Murine-selective STING agonist

Target STING Agonists
CAS 38609-97-1
Purity 98%
Chemical Name or Material 9-Oxo-10(9H)-acridineacetic acid
Recommended Storage Store at 4°C
Synonym ERIS, hMITA, MITA, mitochondrial mediator of IRF3 activation, MPYS, NET23, N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner, sting, transmembrane protein 173
Molecular Formula C15H11NO3
Formula Weight 253.25
7

Tocris Bioscience™ Ibrutinib

Potent and selective BTK inhibitor (IC50= 0.5 nM)

CAS 936563-96-1
Purity 98%
Chemical Name or Material 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one
Recommended Storage Store at -20°C
Synonym Agammaglobulinaemia tyrosine kinase, AGMX1, ATKIMD1, B-cell progenitor kinase, BPK, Bruton agammaglobulinemia tyrosine kinase, Bruton tyrosine kinase, dominant-negative kinase-deficient Brutons tyrosine kinase, tyrosine-protein kinase
Molecular Formula C25H24N6O2
Formula Weight 440.5
8

Invitrogen™ Ionomycin, Calcium Salt

Ionomycin is an effective Ca2+ ionopohre that is commonly used to both modify intracellular Ca2+ concentrations and to calibrate fluorescent Ca2+ indicators when studying the regulatory properties of Ca2+ in cellular processes.

Promotions are available
EDGE
9

Invitrogen™ Nile Red

For use with fluorescence microscopy

Promotions are available
EDGE
10

Guanidine Hydrochloride (Colorless-to-White Crystals), Fisher BioReagents™

For isolation of RNA from cell extracts

Promotions are available
CAS 50-01-1
Color White
Purity ≥99.5%
Physical Form Solid
Chemical Name or Material Guanidine Hydrochloride
Recommended Storage Store at Room Temperature
Synonym guanidine hydrochloride
Merck Index 15, 4597
Molecular Formula CH6ClN3
Formula Weight 95.53
Melting Point 178°C
Assay Percent Range ≥99.5%
11

Molecular Probes™ Probenecid, Water Soluble

Probenecid, Water Soluble

Promotions are available
EDGE
12

Thermo Scientific Chemicals Melanin, synthetic

CAS: 8049-97-6 Molecular Formula: C18H10N2O4

CAS 8049-97-6
Molecular Formula C18H10N2O4
13

Invitrogen™ Octadecyl Rhodamine B Chloride (R18)

Lipophilic octadecyl rhodamine B binds to membranes with fluorophore at aqueous interface and alkyl tail protruding into lipid interior

Promotions are available
14

Invitrogen™ Pepstatin A, BODIPY™ FL Conjugate

For the study of cathepsin D trafficking in cells by fluorescence microscopy

Promotions are available
15

Invitrogen™ Thapsigargin

Tumor promoter

Shipping Condition Room Temperature
Product Type Inhibitor
Recommended Storage Store in freezer (-5°C to -30°C)
Molecular Formula C34H50O12
Label Type Unlabeled