Test
Broad spectrum, irreversible inhibitor of serine proteases
Inhibits NF-κB activation
Potent and selective negative allosteric modulator at mGlu1; also mGlu1 inverse agonist
Potent and selective polynucleotide kinase/phosphatase (PNKP) inhibitor
Potent VEGFR inhibitor; also inhibits other RTKs
Potassium channel modulator; exerts subtype-specific effects
MEK inhibitor
S1P2 receptor antagonist
Glucokinase activator
Stabilizes G-quadruplexes; induces DNA damage and cell cycle arrest
Potent and selective Lck and Src inhibitor; also inhibits SIK
Highly selective and potent non-peptide NPY Y5 receptor antagonist
Potent and selective K2P3.1 (TASK-1) channel blocker
Potent ROCK inhibitor
Antimicrobial peptide derivative of human cathelicidin